Controlled-release vaginal vitamin C tablets Prevegyne® is recognized by the SOGC and clinically proven to help reduce/relieve symptoms of non-specific vaginitis/bacterial vaginosis

Available without a prescription at the pharmacy counter.

Usual dose

Dosing Considerations

Prevegyne® is for vaginal use only. It should not be taken by mouth.

Recommended Dose and Dosage Adjustment

The recommended dosage to help reduce/relieve symptoms of bacterial vaginosis is one (1) Prevegyne® vaginal tablet per day.

A six (6)-day course of treatment is recommended to restore physiological pH and normal vaginal flora. If, after six (6) days, you are still experiencing symptoms or if your symptoms worsen while using Prevegyne®, please consult a healthcare professional.

Missed Dose

If you miss a dose, insert one (1) vaginal tablet as soon as possible. Regular schedule can be resumed the following day. It is important that only one (1) Prevegyne® tablet be inserted daily or within a 24-hour period. Therefore, dose should not be doubled, nor should two (2) tablets be inserted at once to compensate for the missed dose.

Administration

Prevegyne® tablets contain a special vaginal formulation capable of slowly releasing moderate amounts of ascorbic acid over several hours.

In order to decrease the risk of tablets breaking, localized pressure should be applied at the edge of the blister packaging (direct pressure in the center of the tablet should be avoided). The tip of a spoon or a fingernail may be used to gently break the foil underneath the blister.

Prevegyne® tablets should not be intentionally crushed or split. In the event that a tablet is accidently split, both halves of the tablet should be inserted to ensure complete dosage administration. For increased comfort, each half should be inserted round end first.

To ease insertion, it is recommended that Prevegyne® tablets be inserted while in a lying position, using the vaginal applicator or the index and/or middle finger, preferably at bedtime to avoid vaginal leakage.

Consumer Information leaflet

How to insert Prevegyne®

Option 1: Using the included applicator

Before inserting a vaginal Prevegyne® tablet, wash your hands thoroughly. Make sure both pieces of the applicator have been cleaned using a fragrance free-soap, rinsed and dried with a clean cloth.
Delicately remove one (1) tablet from the blister package. To minimize the risk of breaking the tablet, localized pressure should be applied at the edge of the blister (direct pressure in the center of the tablet should be avoided). The tip of a spoon or a fingernail may be used to gently break the foil underneath the blister.
Gently pull back the inner part of the applicator until you feel slight resistance. Place tablet vertically in the top of the applicator. To prevent tablet from falling, ensure that approximately 2/3 of the tablet fits within the top of applicator.To ease insertion, it is recommended that tablets be inserted while lying down, preferably at bedtime.
In a lying position, gently insert the applicator into your vagina as far as it will comfortably go. Holding the applicator in place, gently push the inner part of the applicator into the outer part. This will release the tablet into the vagina. Remove the applicator.

Make sure to wash your hands and clean both pieces of the applicator with warm water and fragrance-free soap after each insertion. To clean, pull apart inside and outside pieces of applicator.

Once completely dry, gently push the inner part into the outer part of the applicator. Make sure to keep applicator clean until next use.

The applicator is for personal use only. To prevent infections, it should not be shared with others.

Dispose of the applicator after completion of the six (6)-day treatment.

Option 2: Without applicator

Wash your hands thoroughly before and after inserting Prevegyne® vaginal tablets.
Delicately remove one (1) tablet from the blister package. To minimize the risk of breaking the tablet, localized pressure should be applied at the edge of the blister (direct pressure in the center of the tablet should be avoided). The tip of a spoon or a fingernail may be used to gently break the foil underneath the blister.
In a lying position, insert one (1) Prevegyne® tablet into your vagina, as far as it will comfortably go, using your index and/or middle finger.
Wash your hands thoroughly after inserting Prevegyne® vaginal tablets.

Overdose

Vitamin C inserted in the vagina is not absorbed in significant amounts. However, only one (1) tablet should be inserted vaginally per day.

Consumer Information leaflet

Side effects

The most common adverse reactions associated with Prevegyne® are vaginal itching and burning. Other side effects associated with Prevegyne® may include vaginal discharge, pain or insomnia.

This is not a complete list of side effects.

Should you experience any unexpected side effects while taking Prevegyne® contact your doctor, pharmacist or other healthcare professional.

Consumer Information leaflet

Reporting suspected side effects

You can report any suspected adverse reactions associated with the use of any health product to the Canada Vigilance Program in one of the following 3 ways:

Note: Consult your health professional who could offer additional information that may be useful in reporting a side effect.

Consumer Information leaflet

Warnings and precautions

If you have never been diagnosed with non-specific vaginitis/bacterial vaginosis, it is recommended that you consult your doctor, pharmacist or other healthcare professional.

For vaginal use only. Do not swallow.

BEFORE you use Prevegyne® talk to your doctor, pharmacist or other healthcare professional if you:

  • have a vaginal infection due to Candida (“yeast infection”)
  • are taking anticoagulants (blood thinners)
  • have hemolytic anemia (premature destruction of red blood cells)
Consumer Information leaflet

Drug interactions

No interactions have been established with the intravaginal use of Prevegyne®.

Consumer Information leaflet

How to store Prevegyne®

Prevegyne® should be stored:

  • at room temperature
  • in a dry place
  • out of reach and sight of children
Consumer Information leaflet

About Duchesnay

Duchesnay is a specialty pharmaceutical company with a long-standing commitment to women’s health. In addition to filling the void in terms of scientific research, education and information and developing pharmacological solutions that are safe for use during pregnancy and breastfeeding, Duchesnay is equally committed to ensuring women’s health and improving their quality of life at every stage.

Thus, Duchesnay has broadened its portfolio of products to offer safe and effective therapeutic options that meet the health and quality of life needs of women and their family members at different stages of their lives.

To learn more about Duchesnay, visit duchesnay.com